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Plot shows the average normalized pixel intensity for each of the 4 replicate pools for each treatment. For each treatment condition, n = 4 replicates, with 2-11 dmd−/− embryos in each replicate. Chemicals were used between 0.5 μM and 4 μM, over two separate experiments. a Graph of average normalized pixel intensities for treatments of dmd mutants with doses of oxamflatin and salermide. Oxamflatin and salermide have dose-dependent effects, independent of dystrophin expression.
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